U.S. Centers for Disease Control and Prevention Director Susan Monarez has been fired, the White House said on Wednesday, less than a month after being sworn in, and four senior officials have resigned amid growing tensions over vaccine policies and public health directives.
Secretary of Health and Human Services Robert F. Kennedy Jr. has made sweeping changes to vaccine policies, including withdrawing federal recommendations for COVID shots for pregnant women and healthy children in May, and firing all members of the CDC's expert vaccine advisory panel in June whom he replaced with hand-picked advisers including fellow anti-vaccine activists.
One of the officials who quit said the CDC's vaccination recommendations were putting young Americans and pregnant women at risk.
White House spokesman Kush Desai late on Wednesday said Monarez was not "aligned with the President's agenda of Making America Healthy Again".
Since she had "refused to resign despite informing HHS leadership of her intent to do so, the White House has terminated Monarez from her position with the CDC," Desai said.
Monarez's attorneys, Mark S. Zaid and Abbe David Lowell, denied she had resigned or had been fired, adding in a statement that "as a person of integrity and devoted to science, she will not resign."
Monarez's attorneys accused Kennedy of targeting her for refusing to support "unscientific directives" and dismiss health experts.
CDC Chief Medical Officer Debra Houry and National Center for Immunization and Respiratory Diseases Director Demetre Daskalakis have resigned, Houry told Reuters. They cited a rise in health misinformation especially on vaccines, attacks on science, the weaponization of public health, and attempts to cut the agency's budget and influence in their resignation letters, reviewed by Reuters.
National Center for Emerging and Zoonotic Infectious Diseases Director Daniel Jernigan also stepped down, days after the agency reported the first U.S. human case of screwworm linked to an ongoing outbreak in Central America. Jen Layden, Director of the CDC Office of Public Health Data, Surveillance and Technology, has also resigned, NBC News reported.
"Recently, the overstating of risks and the rise of misinformation have cost lives, as demonstrated by the highest number of U.S. measles cases in 30 years and the violent attack on our agency," Houry wrote in her resignation.
Budget cuts proposed by President Donald Trump's administration and plans by Kennedy to reorganize the agency would harm its ability to address these challenges.
'Ongoing weaponisation'
The White House sought to cut the CDC's budget by almost $3.6 billion, leaving it with a $4 billion 2026 budget, and Kennedy announced a layoff plan earlier this year that cut 2,400 CDC employees, though some 700 were rehired.
"I am not able to serve in this role any longer because of the ongoing weaponizing of public health," Daskalakis wrote. He declined to comment for this story.
HHS did not provide a reason for Monarez's departure from the agency and did not address the resignations.
"Susan Monarez is no longer director of the Centers for Disease Control and Prevention. We thank her for her dedicated service to the American people," a posting on the department's official X account said.
The CDC has faced mounting challenges under Kennedy’s leadership, including a shooting at its Atlanta headquarters earlier this month. The union representing CDC workers said the incident "compounds months of mistreatment, neglect, and vilification that CDC staff have endured."
Fiona Havers, a former CDC official who resigned in June over vaccine policy, described the recent resignations as "devastating for the CDC," adding that the departing leaders acted as a "buffer between career CDC scientists and RFK Jr. and this administration's attacks on public health."
Sweeping changes
In a pointed resignation letter addressed to Houry and posted by Daskalakis on X Wednesday evening, Daskalakis said the CDC's vaccination recommendations were putting young Americans and pregnant women at risk and disparaged Kennedy's decision to fire the panel.
He said the health agency's policies would return America to a pre-vaccine era where only the strong survive, risking the well-being and security of the country.
Kennedy announced further changes to COVID vaccine eligibility on Wednesday.
Monarez, a federal government scientist, was confirmed by the U.S. Senate on July 29 after Trump nominated her earlier in the year and was sworn in by Kennedy on July 31.
She was Trump's second nominee for the role after he withdrew his nomination in March of former Republican congressman and vaccine critic Dave Weldon, a Kennedy ally, just hours before his scheduled confirmation hearing.
Monarez's comments during her confirmation hearing, in which she said she has not seen evidence linking vaccines and autism, contrasted her with Kennedy, who has promoted the discredited claim of such a link.
Kennedy has launched a department-wide effort to investigate the causes of the condition and said on Wednesday there would be news soon on that front.
"We have announcements that are coming out in September on autism of changes that we are going to make that will dramatically impact the effects," he said during an event with Texas Governor Gregg Abbott.